GeneSight

What is GeneSight genetic testing?

GeneSight is a pharmacogenomic test that analyzes key genetic markers to determine how a person may metabolize or respond to certain psychiatric medications. The test focuses on how genes may influence the effectiveness or tolerability of medications prescribed for depression, anxiety, ADHD, bipolar disorder, and other mental health conditions. It is particularly useful for individuals who have tried multiple medications without success or who have experienced unwanted side effects.

The testing process is simple, safe, and non-invasive—typically requiring only a cheek swab that is completed in minutes at a provider’s office or at home. The sample is then sent to a certified lab, where it is analyzed using advanced technology to produce a detailed report for your provider at Open Mind Psychiatry.

How does GeneSight work?

GeneSight works by evaluating variations in DNA that can affect how the body breaks down and responds to medications. These variations are categorized into three key areas:

• Pharmacokinetics: How quickly or slowly the body metabolizes certain medications
• Pharmacodynamics: How the medication interacts with specific receptors or targets in the brain
• Gene-drug interactions: How specific genes may impact the efficacy or side effect profile of a given drug

Once the genetic data is processed, a comprehensive report is generated. This report places medications into categories based on the individual’s genetic profile—such as “use as directed,” “use with caution,” or “use with increased monitoring.” This guidance allows your provider to make more informed prescribing decisions.

How can GeneSight help to improve the care I receive?

GeneSight testing can significantly improve the quality and precision of psychiatric care. By identifying which medications are more likely to be effective or better tolerated, patients may experience faster symptom relief, fewer adverse effects, and less frustration with their treatment journey.

For those with treatment-resistant depression or complex medication histories, GeneSight offers valuable clarity. Instead of guessing which medication might work, providers can use genetic insights to develop a personalized treatment plan with greater confidence. This proactive approach helps streamline care, enhance medication adherence, and improve long-term mental health outcomes.

To learn more about how GeneSight genetic testing can support better mental health treatment, call Open Mind Psychiatry or request an appointment online today.